Endocrine Abstracts

A 31-year-old lady was referred to the outpatient endocrine clinic for subfertility, intermittent galactorrhoea and amenorrhoea since birth of her son 5 year ago. However, she denied visual disturbances and headache. She was struggling to lose weight but she had no clinical features suggestive of corticosteroid or growth hormone excess apart from an increase in her UK shoe size from 5.5 to 6.5 and family members noted her hands were slightly bigger. She was on an antidepressan...

Introduction: The effects of maternal suboptimal gestational thyroid function (SGTF) on age 3 offspring’s cognitive function were investigated in the Controlled Antenatal Thyroid Screening (CATS) randomised trial, comparing SGTF mothers who received (SGTF-T), or didn’t (SGTF-U), levothyroxine during pregnancy. The analysis was repeated at age 9 in the CATS-II follow-up study, also including children of mothers with normal gestational thyroid function (NGTF). Here we ...

Objectives: The Controlled Antenatal Thyroid Screening (CATS) study I was a randomised trial investigating the effects of levothyroxine treatment for suboptimal gestational thyroid function (SGTF), evaluating mothers with normal gestational thyroid function (NGTF), SGTF who received (SGTF-T), or didn’t (SGTF-U), levothyroxine during pregnancy. The present follow-up study (CATS II) reports the long-term effects of SGTF and levothyroxine treatment on anthropometric and card...